Please use this identifier to cite or link to this item: https://dora.health.qld.gov.au/qldresearchjspui/handle/1/10769
Title: Two-Stage Revision Total Knee Arthroplasty for Melioidosis Prosthetic Joint Infection: A Case Report
Authors: Dadwal, Parvati
Samaraweera, Samitha
Smith, Jon
De Silva, Janath
Smith, Simon 
Hanson, Josh 
Issue Date: 2025
Source: Dadwal P, Samaraweera S, Smith J, De Silva J, Smith S, Hanson J. Two-Stage Revision Total Knee Arthroplasty for Melioidosis Prosthetic Joint Infection: A Case Report. JBJS Case Connect. 2025 May 30;15(2). doi: 10.2106/JBJS.CC.25.00051. PMID: 40446081.
Journal Title: JBJS case connector
Journal: JBJS Case Connect
Abstract: Burkholderia pseudomallei can kill up to 40% of individuals who develop symptoms, but the pathogen has rarely been reported as a cause of prosthetic joint infection (PJI). We report a case of a woman with cultured-confirmed B. pseudomallei knee PJI who survived her infection and had excellent functional recovery after a 2-stage revision, 8 weeks of intravenous ceftazidime followed by 6 months of oral trimethoprim-sulfamethoxazole. Eight years later, she had no postoperative complications, no relapse, and an Oxford Knee Score of 34. B. pseudomallei PJI is rare but life-threatening. Two-stage revision and long-term antibiotic therapy are recommended to effect cure.
Description: Cairns & Hinterland Hospital and Health Service (CHHHS) affiliated authors: Simon Smith, Josh Hanson
DOI: 10.2106/JBJS.CC.25.00051
Keywords: prosthetic joint infection;melioidosis
Type: Article
Appears in Sites:Cairns & Hinterland HHS Publications
Queensland Health Publications

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