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Title: | Type 2 and type 17 effector cells are increased in the duodenal mucosa but not peripheral blood of patients with functional dyspepsia | Authors: | Burns, Grace L Bruce, Jessica K Minahan, Kyra Mathe, Andrea Fairlie, Thomas Cameron, Raquel Naudin, Crystal Nair, Prema M Potter, Michael D E Irani, Mudar Zand Bollipo, Steven Foster, Robert Gan, Lay T Shah, Ayesha Koloski, Natasha A Foster, Paul S Horvat, Jay C Veysey, Martin Holtmann, Gerald Powell, Nick Walker, Marjorie M Talley, Nicholas J Keely, Simon |
Issue Date: | 2022 | Journal: | Frontiers in immunology | Abstract: | Functional dyspepsia is characterised by chronic symptoms of post-prandial distress or epigastric pain not associated with defined structural pathology. Increased peripheral gut-homing T cells have been previously identified in patients. To date, it is unknown if these T cells were antigen-experienced, or if a specific phenotype was associated with FD. | DOI: | 10.3389/fimmu.2022.1051632 | metadata.dc.rights.holder: | Holtmann, Gerald | Keywords: | T cells;functional dyspepsia;functional gastrointestinal disorder (FGID);immunology;lymphocytes | Type: | Article |
Appears in Sites: | Gastroenterology and Hepatology, Princess Alexandra Hospital |
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