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Title: Ibuprofen-related renal tubular acidosis in pregnancy
Authors: Mallett, andrew 
Lynch, Matthew
John, George 
Healy, Helen 
Lust, Karin 
Issue Date: Sep-2011
Journal: Obstetric Medicine (1753-495X)
Abstract: Ibuprofen-related renal tubular acidosis (RTA) has not been previously described in pregnancy but its occurrence outside of pregnancy is being increasingly described. In this case, a 34-year-old woman presented in the third trimester of pregnancy with Type 1 or distal RTA related to ibuprofen and codeine abuse. It was complicated by acute on chronic renal dysfunction and hypokalemia. Delivery at 37 weeks gestation due to concerns of evolving preeclampsia resulted in the birth of a healthy neonate. RTA and hypokalemia were remediated and ibuprofen and codeine abuse ceased. Some renal dysfunction however continued. Thorough and repeated history taking as well as vigilance for this condition is suggested.
DOI: 10.1258/om.2011.110041
metadata.dc.rights.holder: Karin Lust
Keywords: Acidosis, Renal Tubular;RTA;Ibuprofen;Pregnancy;Pre-Eclampsia;Nephrology;Perinatology;Pharmacology, Clinical
Type: Article
Appears in Sites:North West HHS Publications

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