Please use this identifier to cite or link to this item: https://dora.health.qld.gov.au/qldresearchjspui/handle/1/6294
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dc.contributor.authorNicolas Smollen
dc.contributor.authorAl Imam MHen
dc.contributor.authorShulz Cen
dc.contributor.authorBooy Ren
dc.contributor.authorKhandaker Gen
dc.date.accessioned2024-09-24T00:36:33Z-
dc.date.available2024-09-24T00:36:33Z-
dc.date.issued2023-
dc.identifier.urihttps://dora.health.qld.gov.au/qldresearchjspui/handle/1/6294-
dc.description.abstract<h4>Objective</h4>To estimate the effectiveness of vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for protecting people in a largely coronavirus disease 2019 (COVID-19)-naïve regional population from hospitalisation with symptomatic COVID-19.<h4>Design</h4>Retrospective cohort study; analysis of positive SARS-CoV-2 polymerase chain reaction (PCR) test results linked with Central Queensland hospitals admissions data and Australian Immunisation Register data.<h4>Setting, participants</h4>Adult residents of Central Queensland, 1 January - 31 March 2022.<h4>Main outcome measures</h4>Vaccine effectiveness (1 - relative risk of hospitalisation for vaccinated and unvaccinated people) with respect to protecting against hospitalisation with symptomatic COVID-19 after primary vaccination course only (two doses of an approved SARS-CoV-2 vaccine) and after a booster vaccine dose.<h4>Results</h4>Positive SARS-CoV-2 test results were recorded during 1 January - 31 March 2022 for 9682 adults, 7244 of whom had been vaccinated (75%); 5929 people were aged 40 years or younger (62%), 5180 were women (52%). Forty-seven people were admitted to hospital with COVID-19 (0.48%), four required intensive care (0.04%); there were no in-hospital deaths. Vaccine effectiveness was 69.9% (95% confidence interval [CI], 44.3-83.8%) for people who had received only a primary vaccination course and 81.8% (95% CI, 39.5-94.5%) for people who had also received a booster. Of the 665 Aboriginal and Torres Strait Islander adults with positive SARS-CoV-2 test results, 401 had been vaccinated (60%). Six Indigenous people were hospitalised with symptomatic COVID-19 (0.9%); vaccine effectiveness was 69.4% (95% CI, -56.5% to 95.8%) for Indigenous people who had received a primary vaccination course only or the primary course and a booster.<h4>Conclusion</h4>The hospitalisation rate for Central Queensland people with PCR-confirmed Omicron variant SARS-CoV-2 infections during the first quarter of 2022 was low, indicating the protection afforded by vaccination and the value of booster vaccine doses.en
dc.relation.ispartofThe Medical journal of Australiaen
dc.titleThe effectiveness of vaccination for preventing hospitalisation with COVID-19 in regional Queensland: a data linkage study.en
dc.typeArticleen
dc.rights.holderShulz Cen
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.openairetypeArticle-
Appears in Sites:Queensland Health Publications
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